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This definitive work provides a comprehensive treatment of the mathematical background and working methods of three-dimensional reconstruction from tilt series, with Each chapter is a self-contained treatise by a world expert in the author's field of research, resulting in an indispensable resource and companion for laboratories that practice electron tomography or seek to implement electron tomography as a tool for visualization of cells and cell components. Electron tomography : methods for three-dimensional visualization of structures in the cell. [J Frank;] -- Electron tomography has become a standard technique with applications in cell biology, structural biology, and materials science. 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