150. Joint Bayesian inference of risk variants and tissue-specific epigenomic enrichments across multiple complex human diseases ()Li, Kellis. Genome wide association studies (GWAS) provide a powerful approach for uncovering disease-associated variants in human, but fine-mapping the causal variants remains a challenge.
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protein domain is a conserved part of a given
protein sequence and (tertiary) structure that can evolve, function, and exist independently of the rest of the
protein chain.Each domain forms a compact three-dimensional structure and often can be independently stable and folded.Many proteins consist of several structural domains.
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The Origami Revolution.
PBS Airdate: Feburary 15, 2017. NARRATOR: Origami: the ancient art of paper
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Proteins.
Proteins 7.5.1 Explain the four levels of
protein structure, indicating the significance of each level.
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design of new
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design novel activity, behavior, or purpose, and to advance basic understanding of
protein function.Proteins can be designed from scratch (de novo
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