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FMR1 gene contains 17 exons spanning 38 kb. Splice donors and acceptors located in the 5-prime portion of the gene demonstrated greater adherence to consensus than did those in the 3-prime end, providing a possible explanation for alternative splicing in
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small nuclear ribonucleoproteins, are RNA-protein complexes that combine with unmodified pre-mRNA and various other proteins to form a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs. The action of snRNPs is essential to the removal of introns from pre-mRNA, a critical aspect of post-transcriptional modification of RNA ...
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